General Cell Based Assays
Enzo Life Sciences Express DNA methylation kit (shallow well) (2x96wells)
The Express DNA methylation kit (shallow well) features high-throughput (96-well) bisulfite treatment and conversion of DNA for methylation analysis. No preparation is necessary when using the Express Conversion Reagent. Simply add this reagent to a DNA sample and let the reaction proceed to completion. DNA denaturation and bisulfite conversion processes are combined with added heat to facilitate rapid denaturation. Desulphonation and clean-up of the converted DNA is performed using a unique 96-well spin-plate. High yield, converted DNA is ideal for PCR, array, bisulfite and next generation sequencing.
Eurofins Discoverx PathHunter eXpress MC1R U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0861E3CP5L)
The PathHunter MC1R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. α-MSH) based activation of MC1R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MC1R and EA-tagged β-Arrestin-2. Activation of MC1R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress CCKBR CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0191E2CP0L)
The PathHunter CCKBR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. cholecystokinin) based activation of CCKBR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCKBR and EA-tagged β-Arrestin-2. Activation of CCKBR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Indigo Biosciences INDIGO BIOSCIENCES Human PrRPR Reporter Assay Kit, 1x96-well
This PrRPR/GPR10 reporter assay offers precise profiling of receptor activators and inhibitors with exceptional reproducibility. It provides high-quality, quantitative data for lead discovery and optimization. The streamlined workflow delivers actionable results in as little as 24 hr., integrating seamlessly into existing screening pipelines.
- Enables precise profiling of receptor activators and inhibitors.
- Provides high-quality, quantitative data with exceptional reproducibility.
- Streamlined workflow for rapid screening and actionable results in 24 hr.
- Integrates seamlessly into existing screening pipelines.
- Utilizes a luciferase reporter gene to measure drug-induced PrRPR activity.
- Screens test samples to quantify functional interactions against PrRPR.
- Targets PrRPR (GPR10), a Class A Peptide-GPCR family member.
Eurofins Discoverx PathHunter eXpress GHR-JAK1 Functional Assay, 10-Plate Kit. (93-0756E3CP0L)
The PathHunter GHR-JAK1 Functional assay eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting CTKs. This kit assesses GHR activation via detection of JAK1 mediated phosphorylation-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged GHR cytokine receptor, an untagged CTK JAK1 and EA-tagged SH2 domain protein. Upon activation of the cytokine receptor, CTK-based receptor phosphorylation leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human TSLP (IL7R/CRLF2) Dimerization Cell-Based Assay Kit (DLD1)
PathHunter Human TSLP (IL7R/CRLF2) Dimerization Cell-Based Assay Kit (DLD1)
Biotium ALDH1A1 (Aldehyde Dehydrogenase 1A1) (ALDH1A1/1381), Biotin conjugate, 0.1mg/mL
Aldehyde dehydrogenase 1 family member A1 (ALDH1A1), also known as retinal dehydrogenase 1, belongs to the aldehyde dehydrogenase enzyme family, which is involved in the metabolism of alcohol. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than othe
Revvity Health Sciences Inc HTRF Human Total SLP76 Detection Kit, 50,000 Assay Points
HTRF Human Total SLP76 Detection Kit, 50,000 Assay Points
Revvity Health Sciences Inc HTRF Human Phospho-ULK1 (Ser758) Detection Kit, 500 Assay Points
HTRF Human Phospho-ULK1 (Ser758) Detection Kit, 500 Assay Points
Eurofins Discoverx PathHunter eXpress GHR-JAK2 Functional Assay, 10-Plate Kit. (93-0829E3CP14L)
The PathHunter GHR-JAK2 Functional assay eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting CTKs. This kit assesses GHR activation via detection of JAK2 mediated phosphorylation-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged GHR cytokine receptor, an untagged CTK JAK2 and EA-tagged SH2 domain protein. Upon activation of the cytokine receptor, CTK-based receptor phosphorylation leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human & Mouse Total GSK3β Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Total GSK3β Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc LANCE Ultra Phospho-SLP76 (Ser376) Detection Kit, 500 Assay Points
LANCE Ultra Phospho-SLP76 (Ser376) Detection Kit, 500 Assay Points
Agilent Technologies XFE96/XF PRO PDL FLUXPAK MINI
Seahorse XFe96/XF Pro PDL FluxPak Mini. For use with XFe96 and XF Pro Analyzer. Seahorse XFe96/XF Pro PDL FluxPak Mini includes 6 XFe96/XF Pro sensor cartridges, 6 XFe96/XF Pro PDL Cell Culture Microplates, and 1 bottle of Seahorse XF Calibrant Solution 500mL.
TRIBIOSCIENCE INC Lactate Dehydrogenase (LDH) Cytotoxicity Assay Kit, 500 Tests
LDH Cytotoxicity Colorimetric Assay Kit provides the easiest and most accurate approach to measure LDH activity and cytotoxicity of a variety of compounds. The generated signal at OD 460 nm is proportional to the LDH levels of lysed cells.